A multilevel hierarchical framework for quantification of experimental heterogeneity
David James Warne, Xiangrun Zhu, Thomas P. Steele, Stuart T. Johnston, Scott A. Sisson, Matthew Faria, Ryan J. Murphy, Alexander P. Browning
This paper introduces a Bayesian hierarchical framework to quantify both inter- and intra-experimental heterogeneity in dynamical processes using differential equations, demonstrating its robustness and flexibility.
bioRxiv · Dec 23, 2025 · PreprintCell Biology