In silico analysis of predicted differential MHC binding and CD8+ T-cell immune escape of SARS-CoV-2 B.1.1.529 variant mutant epitopes
Pablo Riesgo-Ferreiro, Ranganath Gudimella, Thomas Bukur, Patrick Sorn, Thomas Rösler, Barbara Schrörs, Martin Löwer
The paper analyzes MHC binding and CD8+ T-cell immune escape of SARS-CoV-2 Omicron and Delta variants by comparing epitope binding affinities and identifying mutations affecting immune recognition.
bioRxiv · Jan 31, 2022 · PreprintBioinformatics