A general approach for identifying protein epitopes targeted by antibody repertoires using whole proteomes
Michael L. Paull, Tim Johnston, Kelly N. Ibsen, Joel D. Bozekowski, Patrick S. Daugherty
The paper introduces K-TOPE, a method to identify antibody-binding epitopes across whole proteomes, successfully recovering known epitopes and discovering common viral and bacterial epitopes.
PLoS ONE · Sep 6, 2019Peer-reviewedBioinformatics