Systematic profiling of peptide substrate specificity in N-terminal processing by methionine aminopeptidase using mRNA display and an unnatural methionine analogue
Raphael J. Turra, Satoru Horiya, Mahesh Neralkar, Jennifer K. Bailey, Timothy J. Walsh, Viktor Horváth, Isaac J. Krauss
The paper systematically profiles MAP substrate specificity using mRNA display and N-terminal Met analogues, revealing residue impacts on cleavage efficiency.
ACS Chemical Biology · Jan 8, 2026Peer-reviewedBiochemistry