Modeling the dynamic behaviors of the COPI vesicle formation regulators, the small GTPase Arf1 and its activating Sec7 guanine nucleotide exchange factor GBF1 on Golgi membranes
Garrett Sager, Tomasz Szul, Eunjoo Hwang Lee, Ryoichi Kawai, John F. Presley, Elizabeth S. Sztul
The paper models the dynamic interactions of Arf1 and GBF1 during COPI vesicle formation using FRAP data and simulations, revealing independent membrane association and distinct kinetics.
Molecular Biology of the Cell · Jan 6, 2021Peer-reviewedMolecular Biology