Author

Tomohiro Takano

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Genetic & Genomic Medicine· 2

Signature Assays, Organisms & Methods

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Assay:GWAS summary statistics· 2 Organism:human· 2 Approach:statistical model· 2 Approach:benchmark study· 1 Research Focus:benchmarking· 1 Research Focus:differential expression· 1 Research Focus:gene regulatory network inference· 1 Research Focus:variant effect prediction· 1

Frequent Co-Authors

Alexander G. IoannidisiD· 2 shared Arturo López PinedaiD· 2 shared Babak MoatamediD· 2 shared Carlos D. BustamanteiD· 2 shared Kensuke Numakura· 2 shared Manvi VernekariD· 2 shared Ming Ta Michael LeeiD· 2 shared Nicholas KatsanisiD· 2 shared

Activity by Year

2022-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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2 shared papersGenetic & Genomic Medicine

Alexander G. IoannidisORCID

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2 papers

Recent·Most cited

Polygenic risk score portability for common diseases across genetically diverse populations

Sonia Moreno–Grau, Manvi Vernekar, Arturo López Pineda, Daniel Mas Montserrat, Míriam Barrabés, Consuelo D. Quinto-Cortés, Babak Moatamed, Ming Ta Michael Lee, Zhenning Yu, Kensuke Numakura, Yuta Matsuda, Jeffrey D. Wall, Alexander G. Ioannidis, Nicholas Katsanis, Tomohiro Takano, Carlos D. Bustamante

This study evaluates polygenic risk score (PRS) performance across four ancestry groups for 14 diseases, finding that ancestry-specific PRS models improve accuracy and identifying cross-trait interactions.

Human Genomics · Sep 1, 2024Peer-reviewedGenetic & Genomic Medicine

Validating and automating learning of cardiometabolic polygenic risk scores from direct-to-consumer genetic and phenotypic data: implications for scaling precision health research.

Arturo López Pineda, Manvi Vernekar, Sonia Moreno–Grau, Agustin Rojas‐Muñoz, Babak Moatamed, Ming Ta Michael Lee, Marco A. Nava-Aguilar, Gilberto Gonzalez-Arroyo, Kensuke Numakura, Yuta Matsuda, Alexander G. Ioannidis, Nicholas Katsanis, Tomohiro Takano, Carlos D. Bustamante

This study validates and automates polygenic risk score (PRS) development for cardiometabolic diseases using direct-to-consumer genetic and phenotypic data, showing comparable performance to larger clinical datasets.

Human Genomics · Sep 8, 2022Peer-reviewedGenetic & Genomic Medicine