Biochemical state in tissue can be detected through ultrasound signal
Kazuyo Ito, Yuta Iijima, Tomoki Misumi, Gen Hayase, Kazuki Tamura, Kenji Ikushima, Daisuke Yoshino
This study uses ultrasound imaging to monitor biochemical and structural changes in cancer spheroids over 15 days, revealing necrotic core formation and biomechanical influences on spheroid organization.
npj Biomedical Innovations. · Jun 13, 2025Peer-reviewedBioengineering