Population-scale Y chromosome assemblies reveal recurrent remodeling within constrained architectures
Pille Hallast, Arang Rhie, Mark G. Loftus, Mariateresa Mazzetto, Peter Ebert, Shenghan Gao, Gianni V. Martino, Peter A. Audano, Hufsah Ashraf, Karol Pál, Rebecca Siford, Jana Ebler, Sergey Koren, DongAhn Yoo, Kwondo Kim, , Charles Lee
The paper presents a population-scale Y chromosome reference panel with 142 assemblies, revealing structural and epigenetic variation across 180,000 years of evolution.
bioRxiv · Oct 6, 2026 · PreprintGenomics