Mariateresa Mazzetto

The paper presents a population-scale Y chromosome reference panel with 142 assemblies, revealing structural and epigenetic variation across 180,000 years of evolution.

This study identifies SPINK1 as a regulator of epigenomic states and stemness in PDAC through its interaction with COL18A1 and endostatin release.

The paper identifies chromatin regulatory factors in C. elegans germline that influence zygotic transcription activation during oocyte-to-embryo transition.

The paper defines chromatin states in C. elegans germ nuclei using histone modification and chromatin accessibility data, showing dynamic changes during germ cell differentiation.

This study shows that reduced proteasome activity in aging brains leads to ribosome stoichiometry loss and aggregation, increasing mortality risk in killifish.

The paper identifies ZNF367 as an age-regulated zinc finger factor that modulates embryonic neurogenesis and may contribute to age-related decline in neural stem cell function.