Pathway-Specific Polygenic Scores Improve Cross-Ancestry Prediction of Psychosis and Clinical Outcomes
Justin D. Tubbs, Perry B.M. Leung, Yuanxin Zhong, Na Zhan, Tomy C.K. Hui, Karen K. Y. Ho, Karen S. Y. Hung, Eric F.C. Cheung, Hon‐Cheong So, Simon S. Y. Lui, Pak Chung Sham
This study shows pathway-specific polygenic scores improve cross-ancestry prediction of psychosis risk and clinical outcomes compared to genome-wide polygenic scores.
medRxiv · Sep 1, 2023 · PreprintGenetic & Genomic Medicine