Toon Lemmens

Parallel DNA Holliday Junctions: Myth or Reality? An Atomistic Molecular Dynamics Study

This study uses molecular dynamics simulations to investigate whether parallel Holliday junctions exist in solution, finding they are thermodynamically metastable but rarely observed.

The Kink-Turn Motif: A Powerful Test for Revealing Weaknesses in RNA Force Fields

This paper evaluates RNA force fields by testing their ability to simulate the kink-turn motif, finding that some perform better than others in capturing its structural features.

How Binding Site Flexibility Promotes RNA Scanning in TbRGG2 RRM: A Molecular Dynamics Simulation Study

This study uses molecular dynamics simulations to show how TbRGG2 RRM binds uridine-rich RNAs through dynamic binding modes and auxiliary states, enabling efficient scanning while maintaining selectivity.