Stably Accelerating Stiff Quantitative Systems Pharmacology Models: Continuous-Time Echo State Networks as Implicit Machine Learning
R. Anantharaman, A. Abdelrehim, A. Jain, A. Pal, D. Sharp, U. Utkarsh, C. V. Rackauckas
This paper introduces continuous-time echo state networks (CTESNs) to accelerate stiff quantitative systems pharmacology models, achieving up to 56x speedup with <5% error.
bioRxiv · Oct 10, 2021Pharmacology & Toxicology