Mathematical modeling of the role of α-synuclein and dopamine in cell death in Parkinson’s disease provides the molecular basis to the toxicity of different point mutations
Gourvendu Saxena, Utkarsh Khandelwal, Mukesh Doble
The paper models the role of α-synuclein and dopamine in cell death in Parkinson’s disease, showing how mutations affect toxicity through oxidative stress and dopamine pathways.
bioRxiv · Jul 25, 2019 · PreprintSystems Biology