Signal peptide efficiency: from high-throughput data to prediction and explanation
Stefano Grasso, Valentina Dabene, Margriet M. W. B. Hendriks, Priscilla Zwartjens, René Pellaux, Martin Held, Sven Panke, Jan Maarten van Dijl, Andreas Meyer, Tjeerd van Rij
The paper evaluates 12,000 signal peptides using a high-throughput assay, trains a machine learning model to predict secretion efficiency, and explains the model's features.
ACS Synthetic Biology · Jan 17, 2023Peer-reviewedSynthetic Biology