Development and cross-cohort evaluation of a multimodal deep-learning model for ER, PR and HER2 status classification in breast cancer
Binh Minh Tran, Van An Nguyen, Quynh Anh Dang, Ngoc Minh Hai Nguyen, Quang Anh Nguyen, Hai Nam Tran, Dang Hung Tran, Thi Bich Van Nguyen
This paper develops a multimodal deep-learning model for breast cancer biomarker classification and evaluates its performance across cohorts, finding high discrimination but limited incremental value over a simpler transcript-based model.
bioRxiv · Nov 3, 2026 · PreprintBioinformatics