Author

Varun Reddy

University of Waterloo

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

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Cancer Biology· 1

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Approach:biophysical modeling· 1 Organism:human· 1 Research Focus:protein folding & dynamics· 1 Assay:protein structure· 1

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Aravindhan GanesaniD· 1 shared Norman LyiD· 1 shared

Activity by Year

2026-2026 · peak 1/yr

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1 shared paperCancer Biology

Aravindhan GanesanORCID

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1 paper

Recent·Most cited

Membrane-coupled conformational switching of VISTA regulates immune checkpoint signaling via CC' loop accessibility

Aravindhan Ganesan, Varun Reddy, Norman Ly

This study uses molecular dynamics simulations to show that VISTA's conformational switching between Up and Down states regulates its immune checkpoint function through CC' loop accessibility.

bioRxiv · Feb 10, 2026 · PreprintCancer Biology