Author

Vlad Fedotov

Skolkovo Institute of Science and Technology

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Biology Disciplines

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Systems Biology· 1

Signature Assays, Organisms & Methods

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Organism:human· 1 Approach:statistical model· 1

Frequent Co-Authors

Dmitrii V. KriukoviD· 1 shared Ekaterina E. KhrameevaiD· 1 shared Evgeniy EfimoviD· 1 shared Leonid G. MalaeviD· 1 shared

Activity by Year

2026-2026 · peak 1/yr

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4 top collaborators · 6 mutual co-author links

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1 shared paperSystems Biology

Dmitrii V. KriukovORCID

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1 paper

Recent·Most cited

Somatic mutations impose an entropic upper bound on human lifespan

Evgeniy Efimov, Vlad Fedotov, Leonid G. Malaev, Ekaterina E. Khrameeva, Dmitrii V. Kriukov

The paper estimates human lifespan limits by modeling the impact of somatic mutations, finding they reduce lifespan from 430 to 169 years but cannot fully explain mortality.

npj Aging · Jun 25, 2026Peer-reviewedSystems Biology