Large-Scale Genomic Analysis of CpG-Mediated Immunogenicity in Bacteriophages and a Novel Predictive Risk Index
Lukeman Kharrat, Camilo García-Botero, Wade Ingersoll, Tiffany Luong, Alejandro Reyes, Dwayne R. Roach
This paper introduces the Bacteriophage Risk Index (BRI) to predict phage immunogenicity using CpG features, validated through experimental testing and genome-wide analysis.
bioRxiv · May 15, 2025 · PreprintImmunology