scCaT: an explainable capsulating architecture for sepsis diagnosis transferring from single-cell RNA sequencing
Xubin Zheng, Dian Meng, Duo Chen, Wan-Ki Wong, Ka-Ho To, Lei Zhu, Jiarui Wu, Yining Liang, Kwong‐Sak Leung, Man‐Hon Wong, Lixin Cheng
This paper introduces scCaT, a deep learning framework combining capsulating architecture and Transformer for sepsis diagnosis using single-cell RNA sequencing data and transferring to bulk RNA data, achieving high accuracy and explainability.
PLoS Computational Biology · Oct 21, 2024Peer-reviewedBioinformatics