Quantitative analysis of cryptic splicing associated with TDP-43 depletion
Jack Humphrey, Warren Emmett, PIetro Fratta, Adrian M. Isaacs, Vincent Plagnol
The paper quantifies cryptic exon inclusion in TDP-43 depleted datasets and shows they are bound by TDP-43 and not linked to FUS, with implications for ALS/FTD pathogenesis.
BMC Medical Genomics · May 26, 2017Peer-reviewedGenomics