MicroRNA-122 supports robust innate immunity in hepatocytes by suppressing STAT3 phosphorylation
Hui Min Xu, Shi‐Jun Xu, Shu‐Juan Xie, Yin Zhang, Jianhua Yang, Wei-Qi Zhang, Man-Ni Zheng, Hui Zhou, Liang‐Hu Qu
This study shows miR-122 enhances hepatocyte innate immunity by reducing STAT3 phosphorylation, thereby increasing interferon production against HCV and poly(I:C).
bioRxiv · Jan 19, 2018 · PreprintMolecular Biology