A Multi-Objective Scoring (MOS) Framework for Detecting Cross-Modal Spatial Similarity: Conceptual and Direct Formulations
Amin Jarrahi, A. Warren Jones, Weisheng Tang, Hairong Qi, Anna Colleen Crouch
The paper introduces a Multi-Objective Scoring framework to detect cross-modal spatial similarity between spatial transcriptomics and MSI data without requiring exact alignment, showing strong performance on synthetic and real datasets.
bioRxiv · Apr 13, 2026 · PreprintBiochemistry