Predicting Gene Spatial Expression and Cancer Prognosis: An Integrated Graph and Image Deep Learning Approach Based on HE Slides
Ruitian Gao, Xin Yuan, Yanran Ma, Ting Wei, Luke J. Johnston, Yanfei Shao, Wenwen Lv, Tengteng Zhu, Yue Zhang, Junke Zheng, Guoqiang Chen, Jing Sun, Yu Guang Wang, Zhangsheng Yu
The paper introduces an IGI-DL model that predicts gene spatial expression from HE images and improves cancer prognosis using a risk score derived from predicted gene expression.
Cell Reports Medicine · May 1, 2024Peer-reviewedBioinformatics