Author

William McCusker

Ginkgo Bioworks, Inc. (United States)

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Synthetic Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 1 Approach:machine learning (classical)· 1

Frequent Co-Authors

Ahmed El-KishkyiD· 1 shared Alexus A. Smith· 1 shared Alicia Byrn· 1 shared Alvaro R. Bautista-AyalaiD· 1 shared Alycia Wong· 1 shared Alyssa Tran· 1 shared Andrew L. Consiglio· 1 shared Andrew Nesson· 1 shared

Activity by Year

2026-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperSynthetic Biology

Ahmed El-KishkyORCID

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1 paper

Recent·Most cited

Using a GPT-5-driven autonomous lab to optimize the cost and titer of cell-free protein synthesis

Alexus A. Smith, Edmund L. Wong, Ronan C. Donovan, Brad Chapman, Ryan Harry, Pooyan Tirandazi, Paulina Kanigowska, Elizabeth A. Gendreau, Robert H. Dahl, Michal Jastrzebski, Jose E. Cortez, Christopher Bremner, José C. Morales Hemuda, James Dooner, Ian Graves, , Reshma P. Shetty

This paper demonstrates an LLM-driven autonomous lab that reduces the cost of cell-free protein synthesis by 40% and increases titer by 27% through iterative optimization.

bioRxiv · Feb 5, 2026 · PreprintSynthetic Biology