Modeling pathway overlap increases accuracy of GWAS gene set enrichment
Alanna C. Cote, William Reagan Kesting, Judit García‐González, Paul F. O’Reilly
This paper introduces GSR, a method to adjust for pathway overlap in GWAS gene set enrichment, improving the accuracy of identifying biologically relevant pathways.
medRxiv · Sep 7, 2026 · PreprintGenetic & Genomic Medicine