Statistical Approaches to Decreasing the Discrepancy of Non-detects in qPCR Data
Valeriia Sherina, Helene R. McMurray, Winslow Powers, Hartmut Land, Tanzy Love, Matthew N. McCall
The paper introduces statistical methods to handle non-detects in qPCR data by modeling missing data mechanisms and using multiple imputation to reduce bias in gene expression estimation.
bioRxiv · Dec 8, 2017 · PreprintBioinformatics