Accurate antibody loop structure prediction enables zero-shot design of target-specific antibodies
Yewon Bang, Yoon‐Aa Choi, Jeonghyeon Gu, Sohee Kwon, Dohoon Lee, Eun Seo Lee, Myeong Sup Lee, Sangchoon Lee, Soyul Lee, Jungsub Lim, Jin Young Maeng, Juno Nam, Jinsung Noh, Hyunjeong Oh, Sun Young Park, , Hasun Yu
This study shows that accurate antibody loop structure prediction enables the design of target-specific antibodies without prior structural templates.
bioRxiv · Aug 23, 2024 · PreprintBioengineering