LFAQ: towards unbiased label-free absolute protein quantification by predicting peptide quantitative factors
Cheng Chang, Zhiqiang Gao, Wantao Ying, Yan Fu, Yan Zhao, Songfeng Wu, Mengjie Li, Guibin Wang, Xiaohong Qian, Yunping Zhu, Fuchu He
LFAQ improves label-free absolute protein quantification by correcting MS intensity biases using predicted peptide quantitative factors, achieving higher accuracy and precision, especially for low-abundance proteins.
Analytical Chemistry · Dec 10, 2018Peer-reviewedBioinformatics