TET2-mediated epigenetic modification promotes stress senescence of pancreatic β cells in type 2 diabetes mellitus
Weijuan Cai, Qingqing Song, Xiaoqing Mo, Huaqian Li, Yuling Song, Liang Yin
This study identifies TET2-mediated epigenetic modification as a mechanism promoting β cell senescence in type 2 diabetes mellitus by regulating PTEN methylation and H4K16ac.
bioRxiv · Nov 1, 2024 · PreprintCell Biology