Author

Xudong Guo

Northwest A&F University

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Biology Disciplines

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Bioinformatics· 2

Signature Assays, Organisms & Methods

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Approach:graph neural network· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:protein structure prediction· 1 Assay:proteomics· 1

Frequent Co-Authors

Fuyi LiiD· 2 shared Heyun SuniD· 2 shared Yi Hao· 2 shared Yue BiiD· 2 shared Zixu RaniD· 2 shared Cong Wang· 1 shared Jiangning SongiD· 1 shared Jose Maria PoloiD· 1 shared

Activity by Year

2026-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 39 mutual co-author links

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2 shared papersBioinformatics

Fuyi LiORCID

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2 papers

Recent·Most cited

Structure-aware geometric graph learning for modeling protease-substrate specificity at scale

Xudong Guo, Yue Bi, Zixu Ran, Tong Pan, Heyun Sun, Yi Hao, Runchang Jia, Cong Wang, Qi Zhang, Lukasz Kurgan, Jiangning Song, Fuyi Li

OmniCleave models protease-substrate specificity using a geometric graph framework, outperforming existing methods and identifying novel substrates.

bioRxiv · Apr 10, 2026 · PreprintBioinformatics

Graph-based RNA structural representation reveals determinants of subcellular localization

Yi Hao, Heyun Sun, Zixu Ran, Xudong Guo, Ming Liu, Yue Bi, Jose Maria Polo, Ning Liu, Fuyi Li

GRASP uses a graph neural network to predict RNA subcellular localization by modeling RNA structure, outperforming existing methods across RNA types and transcript lengths.

bioRxiv · Feb 24, 2026 · PreprintBioinformatics