Measurement of selective constraint on human gene expression
Emily C. Glassberg, Ziyue Gao, Arbel Harpak, Xun Lant, Jonathan K. Pritchard
The paper measures selective constraint on human gene expression by analyzing copy number variants and allele-specific expression data, finding that singletons have larger effects but explain only 5% of cis-regulatory expression heritability.
bioRxiv · Jun 13, 2018 · PreprintGenomics