Epigenetic control of coordinated hematopoietic and cardiovascular development by Rnf2 in zebrafish
This study shows Rnf2 suppresses hematoendothelial progenitor genes in zebrafish, affecting hematopoiesis and cardiogenesis, and its loss leads to increased HSCs and differentiation defects.
bioRxiv · Dec 14, 2020 · PreprintDevelopmental Biology