GenomicsbioRxivPreprint
Somatic epimutations cap genetic determinism in the human diploid chromatin epigenome
Mitchell Robert Vollger, Elliott G. Swanson, Shane J. Neph…·Andrew B. Stergachis
The paper introduces FIRE to comprehensively map haplotype-selective chromatin accessibility in diploid human genomes, revealing somatic epimutations that contribute to non-genetic chromatin alterations.