Chemotherapy drugs induce different gut microbiota disorder pattern and NODs/RIP2/NF-κB signaling pathway activation that lead to different degrees of intestinal injury
Bin Huang, Mengxuan Gui, Jinyan Zhao, Zhuona Ni, Yanbin He, Jun Peng, Jiumao Lin
This study compares the effects of four chemotherapy drugs on gut microbiota and intestinal injury in mice, finding that L-OHP causes the most severe microbiota disruption and NODs/RIP2/NF-κB pathway activation.
bioRxiv · May 4, 2022 · PreprintMolecular Biology