Human biliary atresia extrahepatic cholangiocyte organoids express increased ER and oxidative stress, altered drug metabolism and cell polarity changes
Adi Har‐Zahav, Yara Hamoudi, Keren Danan, Ana Tobar, Michal Basphelchik, Michael Gurevich, Raanan Shamir, Irit Gat‐Viks, Orith Waisbourd‐Zinman
This study identifies molecular alterations in BA-derived extrahepatic cholangiocyte organoids, including ER stress, disrupted polarity, and drug metabolism changes.
Frontiers in Bioengineering and Biotechnology · May 7, 2026Peer-reviewedMolecular Biology