Author

Yifei Shang

Institute of Genetics and Cancer

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioinformatics· 1 Genetics· 1

Signature Assays, Organisms & Methods

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Organism:human· 2 Research Focus:benchmarking· 1 Assay:CRISPR screen· 1 Approach:deep learning· 1 Assay:GWAS summary statistics· 1 Approach:statistical model· 1 Research Focus:variant effect prediction· 1

Frequent Co-Authors

Joseph A. MarshiD· 2 shared Ankit PathakiD· 1 shared Grzegorz R. KudlaiD· 1 shared Hasan ÇubukiD· 1 shared Marcin PlechiD· 1 shared Mihaly BadonyiiD· 1 shared Vahid AslanzadehiD· 1 shared

Activity by Year

2026-2026 · peak 2/yr

Co-Author Collaboration Network

7 top collaborators · 16 mutual co-author links

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2 shared papersGenetics

Joseph A. MarshORCID

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Author profile →

2 papers

Recent·Most cited

Mechanism-selective deep mutational scanning distinguishes ERCC2 disease phenotypes

Hasan Çubuk, Vahid Aslanzadeh, Yifei Shang, Marcin Plech, Ankit Pathak, Grzegorz R. Kudla, Joseph A. Marsh

The paper uses deep mutational scanning to distinguish disease mechanisms in ERCC2 variants, finding that TTD variants have lower fitness than XP variants.

bioRxiv · Sep 27, 2026 · PreprintGenetics

Clinical evidence yield as a framework for evaluating computational predictors and multiplexed assays of variant effect

Yifei Shang, Mihaly Badonyi, Joseph A. Marsh

The paper introduces MES, a metric to evaluate variant effect predictors and MAVEs based on clinical evidence yield, showing discrepancies with AUROC.

bioRxiv · Mar 30, 2026 · PreprintBioinformatics