Author

Yige Chen

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Synthetic Biology· 1

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Organism:E. coli· 1 Research Focus:genome assembly· 1 Approach:variational autoencoder· 1 Assay:whole-genome sequencing· 1

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Anastasiia Shcherbakova· 1 shared Chris P. BarnesiD· 1 shared Claire S. Grierson· 1 shared Daniel W. A. BuchaniD· 1 shared Kieren Sharma· 1 shared Lucia Marucci· 1 shared

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2024-2024 · peak 1/yr

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1 shared paperSynthetic Biology

Anastasiia Shcherbakova

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1 paper

Recent·Most cited

Designing minimal E. coli genomes using variational autoencoders

Anastasiia Shcherbakova, Kieren Sharma, Yige Chen, Claire S. Grierson, Lucia Marucci, Daniel W. A. Buchan, Chris P. Barnes

This study uses variational autoencoders to generate minimal E. coli genomes, finding 6 out of 100 sampled genomes were viable in a computational model.

bioRxiv · Oct 22, 2024 · PreprintSynthetic Biology