Runx3 prevents spontaneous colitis by directingdifferentiation of anti-inflammatory mononuclear phagocytes
Shay Hantisteanu, Yosef Dicken, Varda Negreanu, Dalia Goldenberg, Ori Jacob Brenner, Dena Leshkowitz, Joseph Lotem, Ditsa Levanon, Yoram Groner
This study shows that Runx3 in mononuclear phagocytes prevents colitis by promoting anti-inflammatory differentiation and suppressing pro-inflammatory gene expression.
PLoS ONE · May 26, 2020Peer-reviewedGenetics