Dual Transcriptional Drivers of Immune Suppression in SACC: NOTCH1 for Cellular and MYB for Humoral Immunity
Guoliang Yang, Xudong Wang, Ye Tian, Tingyao Ma, Youmei Chen, Fang Nan, Qian Chen, Lu Kong, Xiaohong Chen
This paper identifies NOTCH1 and MYB as dual transcriptional drivers of immune suppression in salivary adenoid cystic carcinoma, revealing their roles in suppressing T-cell and B-cell immunity through distinct signaling pathways.
bioRxiv · Nov 17, 2025 · PreprintImmunology