Author

Yutaka Saito

Kitasato UniversityPrimary ORCID profile (0000-0002-4853-0153 · 2 papers)Unclaimed ORCID profile · follow to get notified of new preprints

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Yutaka SaitoiD2 papers · Kitasato University;

Biology Disciplines

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Bioinformatics· 3

Signature Assays, Organisms & Methods

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Approach:deep learning· 3 Organism:human· 3 Assay:long-read sequencing· 3 Organism:mouse· 3 Research Focus:sequence-to-function modeling· 3 Organism:bacteria (other)· 2 Assay:CITE-seq· 2 Approach:transformer / foundation model· 2

Frequent Co-Authors

Bian BianiD· 3 shared Yiming Zhang· 2 shared Hongmin LiiD· 1 shared Jichen ZhangiD· 1 shared Jiuzhou Zhong· 1 shared Kiyoshi AsaiiD· 1 shared Kuanhuan Tan· 1 shared Weiqi Yan· 1 shared

Activity by Year

2025-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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3 shared papersBioinformatics

Bian BianORCID

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3 papers

Recent·Most cited

Designing mRNA coding sequence via multimodal reverse translation language modeling with Pro2RNA

Bian Bian, Yiming Zhang, Jichen Zhang, Kiyoshi Asai, Yutaka Saito

Pro2RNA generates species-adapted mRNA coding sequences from protein sequences using a multimodal language model, outperforming existing methods in benchmark tests.

bioRxiv · Mar 20, 2026 · PreprintBioinformatics

Large generative mRNA language foundation model for efficient coding sequence generation and design with mRNA-GPT

Bian Bian, Yiming Zhang, Hongmin Li, Jiuzhou Zhong, Yutaka Saito

The paper introduces mRNA-GPT, a generative mRNA language model trained on sequences from bacteria, eukaryotes, and archaea, showing improved translation efficiency and stability in mRNA design.

bioRxiv · Dec 24, 2025 · PreprintBioinformatics

Large mRNA language foundation modeling with NUWA for unified sequence perception and generation

Yunshan Zhong, Weiqi Yan, Yiming Zhang, Kuanhuan Tan, Yutaka Saito, Bian Bian

This paper introduces NUWA, an mRNA language model that enables unified sequence perception and generation across diverse species and tasks.

bioRxiv · Nov 1, 2025 · PreprintBioinformatics