The mitochondrial calcium uniporter transports Ca2+ via a ligand-relay mechanism.
C. Chan, C.-C. Yuan, J. G. McCoy, P. S. Ward, Z. Grabarek
This study identifies a ligand-relay mechanism in the mitochondrial calcium uniporter (mtCU) driven by structural fluctuations in the DxxE sequence.
bioRxiv · Jun 17, 2023 · PreprintBiochemistry