Author

Z. Gumus

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Biophysics· 1

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Approach:deep learning· 1 Organism:human· 1 Research Focus:protein folding & dynamics· 1 Assay:protein structure· 1 Approach:statistical model· 1

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B. Erman· 1 shared S. Vatansever· 1 shared

Activity by Year

2018-2018 · peak 1/yr

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2 top collaborators · 1 mutual co-author link

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1 shared paperBiophysics

B. Erman

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1 paper

Recent·Most cited

Oncogenic G12D mutation alters local conformations and dynamics of K-Ras

S. Vatansever, B. Erman, Z. Gumus

This study uses molecular dynamics simulations to show that the G12D mutation in K-Ras alters local conformations and dynamics, particularly in Switch-II and 3-helix regions, leading to a catalytically impaired state.

bioRxiv · Nov 12, 2018Biophysics