Author

Zachary A. Castles

Baylor College of Medicine

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Developmental Biology· 1

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Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Organism:plant (other)· 1 Approach:statistical model· 1

Frequent Co-Authors

Amit Dubey· 1 shared Andrea Rauschmayer· 1 shared Blair W. Benham-PyleiD· 1 shared Haleigh Brownlee· 1 shared Hannah M. Ashraf· 1 shared Nirurita Mahadev· 1 shared

Activity by Year

2025-2025 · peak 1/yr

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6 top collaborators · 15 mutual co-author links

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1 shared paperDevelopmental Biology

Amit Dubey

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1 paper

Recent·Most cited

Developmental BiologybioRxivPreprintDec 29, 2025

Activin/TGF-beta signaling levels coordinate whole-body regeneration with genotoxic stress in Schmidtea mediterranea

Haleigh Brownlee, Amit Dubey, Nirurita Mahadev…·Blair W. Benham-Pyle

The paper shows that activin/TGF-beta signaling inhibits regeneration after radiation in planarians, but its depletion restores regeneration by increasing stem cell proliferation despite DNA damage.

DOI 10.64898/2025.12.29.696926

plant (other)bulk RNA-seq