Benchmarking computational methods to identify spatially variable genes and peaks
Zhijian Li, Zain M.Patel, Dongyuan Song, Guanao Yan, Jingyi Jessica Li, Luca Pinello
This study benchmarks 14 computational methods for identifying spatially variable genes and peaks using simulated and real-world spatial transcriptomics and ATAC-seq data, finding spatialDE2 performs best and highlighting the need for specialized algorithms for peaks.
bioRxiv · Dec 2, 2023 · PreprintBioinformatics