Histological aging signatures enable tissue-specific disease prediction from blood
Ernesto Abila, Iva Buljan, Yimin Zheng, Tamás Veres, Zhilong Weng, Maja Carina Nackenhorst, Wolfgang Hulla, Yuri Tolkach, Adelheid Wöehrer, André F. Rendeiro
This paper develops tissue clocks from histopathological images to predict biological age and disease risk from blood samples, showing non-uniform aging rates across tissues and associations with lifestyle and medical factors.
bioRxiv · Nov 14, 2024 · PreprintPhysiology