Integrated analysis reveals neuro-immune pathway in the central nervous system that supports SGLT2is protective effects in treatment of cardiac remodeling
Miao Yuan, Hanxue Wu, Jiawei Wang, Zihan Qiu, Kexin Li, Jiaxi Xu, Dengfeng Gao
This study identifies a neuro-immune pathway in the central nervous system that mediates the protective effects of SGLT2 inhibitors on cardiac remodeling using preclinical and clinical data.
bioRxiv · Oct 2, 2025 · PreprintMolecular Biology