Patient-Derived Circulating Monocytes Promote Calcific Aortic Valve Disease Progression
Léa Di Maria, Hugues Boël, Nicolas Perzo, Sylvanie Renet, Chloé Valentin, Théo Lemarcis, Bryan Marais, Zina Badji, Thomas Lévesque, Delphine M. Béziau, Hélène Eltchaninoff, Ebba Bråkenhielm, Éric Durand, Sylvain Fraineau
This study shows that CAVD patients have monocytes with pro-inflammatory and pro-calcific properties that promote valve disease progression.
bioRxiv · May 4, 2026 · PreprintPathology