Location of ryanodine receptor type 2 mutation predicts age of onset of sudden death in catecholaminergic polymorphic ventricular tachycardia. A systematic review and meta analysis of case based literature
Halil Beqaj, Leah R. Sittenfeld, Alex R. Chang, Marco Miotto, Haikel Dridi, Gloria Willson, Carolyn Martinez Jorge, Jaan Altosaar Li, Steven R. Reiken, Yang Liu, Zonglin Dai, Andrew R. Marks
This study identifies that RyR2 mutation locations in CPVT patients predict earlier onset of sudden death, based on a meta-analysis of 1008 patients from 227 papers.
medRxiv · Mar 15, 2024 · PreprintGenetic & Genomic Medicine