PEPPI: Whole-proteome protein-protein interaction prediction through structure and sequence similarity, functional association, and machine learning
Eric W. Bell, Jacob H. Schwartz, Lydia Freddolino, Yang Zhang
PEPPI predicts protein-protein interactions using structural, sequence, and functional data, achieving higher accuracy than existing methods and identifying interactions relevant to SARS-CoV-2 infection.
Journal of Molecular Biology · Jun 1, 2022Peer-reviewedSystems Biology