Enzyme capacity-based genome scale modelling of CHO cells
Hock Chuan Yeo, Jong Kwang Hong, Meiyappan Lakshmanan, Dong‐Yup Lee
This paper introduces ecFBA, an enzyme capacity-constrained flux balance analysis method, to improve flux prediction accuracy in CHO cells by incorporating enzyme kinetic data.
Metabolic Engineering · Apr 21, 2020Peer-reviewedSystems Biology